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Ubiquitin‐like domains can target to the proteasome but proteolysis requires a disordered region

Ubiquitin and some of its homologues target proteins to the proteasome for degradation. Other ubiquitin‐like domains are involved in cellular processes unrelated to the proteasome, and proteins containing these domains remain stable in the cell. We find that the 10 yeast ubiquitin‐like domains teste...

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Pubblicato in:EMBO J
Autori principali: Yu, Houqing, Kago, Grace, Yellman, Christopher M, Matouschek, Andreas
Natura: Artigo
Lingua:Inglês
Pubblicazione: John Wiley and Sons Inc. 2016
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Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC4884787/
https://ncbi.nlm.nih.gov/pubmed/27234297
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.15252/embj.201593147
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