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Proteasomal degradation from internal sites favors partial proteolysis via remote domain stabilization
The ubiquitin-proteasome system controls the concentrations of hundreds of regulatory proteins and removes misfolded and damaged proteins in eukaryotic cells. The proteasome recognizes ubiquitinated proteins and then engages its substrates at unstructured initiation regions. After initiation, it pro...
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| Main Authors: | , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
2011
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3199294/ https://ncbi.nlm.nih.gov/pubmed/21815694 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/cb2002285 |
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