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DHX9/RHA Binding to the PBS-Segment of the Genomic RNA during HIV-1 Assembly Bolsters Virion Infectivity

Cellular RNA binding proteins incorporated into virions during HIV-1 assembly promote the replication efficiency of progeny virions. Despite its critical role in bolstering virion infectivity, the molecular basis for incorporation of DHX9/RNA helicase A (RHA) to virions remains unclear. Here, cell-b...

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Bibliographische Detailangaben
Veröffentlicht in:J Mol Biol
Hauptverfasser: Boeras, Ioana, Song, Zhenwei, Moran, Andrew, Franklin, Jarryd, Brown, William Clay, Johnson, Marc, Boris-Lawrie, Kathleen, Heng, Xiao
Format: Artigo
Sprache:Inglês
Veröffentlicht: 2016
Schlagworte:
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC4884555/
https://ncbi.nlm.nih.gov/pubmed/27107641
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.jmb.2016.04.011
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