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Attenuation of morphine tolerance and dependence by thymoquinone in mice
OBJECTIVE: Dependence and tolerance are major restricting factors in the clinical use of opioid analgesics. In the present study, the effects of thymoquinone, the major constituent of Nigella sativa seeds, on morphine dependence and tolerance were investigated in mice. MATERIALS AND METHODS: Male ad...
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| Veröffentlicht in: | Avicenna J Phytomed |
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| Hauptverfasser: | , , , , |
| Format: | Artigo |
| Sprache: | Inglês |
| Veröffentlicht: |
Mashhad University of Medical Sciences
2016
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| Schlagworte: | |
| Online Zugang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4884218/ https://ncbi.nlm.nih.gov/pubmed/27247922 |
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