Role of L-arginine/NO/cGMP/K(ATP) channel signaling pathway in the central and peripheral antinociceptive effect of thymoquinone in rats

OBJECTIVE(S): Growing evidence demonstrates that L-arginine/NO/cGMP/K(ATP) channel pathway has a modulatory role in pain perception. Previous studies have shown that thymoquinone exerts antinociceptive effects; however, the mechanisms underlying antinociception induced by thymoquinone have not been...

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Pubblicato in:Iran J Basic Med Sci
Autori principali: Parvardeh, Siavash, Sabetkasaei, Masoumeh, Moghimi, Mahsa, Masoudi, Alireza, Ghafghazi, Shiva, Mahboobifard, Fatemeh
Natura: Artigo
Lingua:Inglês
Pubblicazione: Mashhad University of Medical Sciences 2018
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Original Article
Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC6015243/
https://ncbi.nlm.nih.gov/pubmed/29942454
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.22038/IJBMS.2018.26255.6438
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