A Familial C3GN Secondary to Defective C3 Regulation by Complement Receptor 1 and Complement Factor H

C3 glomerulopathy is a recently described form of CKD. C3GN is a subtype of C3 glomerulopathy characterized by predominant C3 deposits in the glomeruli and is commonly the result of acquired or genetic abnormalities in the alternative pathway (AP) of the complement system. We identified and characte...

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Vydáno v:J Am Soc Nephrol
Hlavní autoři: Chauvet, Sophie, Roumenina, Lubka T., Bruneau, Sarah, Marinozzi, Maria Chiara, Rybkine, Tania, Schramm, Elizabeth C., Java, Anuja, Atkinson, John P., Aldigier, Jean Claude, Bridoux, Frank, Touchard, Guy, Fremeaux-Bacchi, Veronique
Médium: Artigo
Jazyk:Inglês
Vydáno: American Society of Nephrology 2016
Témata:
Basic Research
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC4884110/
https://ncbi.nlm.nih.gov/pubmed/26471127
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1681/ASN.2015040348
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