Anti-Factor B and Anti-C3b Autoantibodies in C3 Glomerulopathy and Ig-Associated Membranoproliferative GN

In C3 glomerulopathy (C3G), the alternative pathway of complement is frequently overactivated by autoantibodies that stabilize the C3 convertase C3bBb. Anti-C3b and anti-factor B (anti-FB) IgG have been reported in three patients with C3G. We screened a cohort of 141 patients with C3G and Ig-associa...

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Veröffentlicht in:J Am Soc Nephrol
Hauptverfasser: Marinozzi, Maria Chiara, Roumenina, Lubka T., Chauvet, Sophie, Hertig, Alexandre, Bertrand, Dominique, Olagne, Jérome, Frimat, Marie, Ulinski, Tim, Deschênes, Georges, Burtey, Stephane, Delahousse, Michel, Moulin, Bruno, Legendre, Christophe, Frémeaux-Bacchi, Véronique, Le Quintrec, Moglie
Format: Artigo
Sprache:Inglês
Veröffentlicht: American Society of Nephrology 2017
Schlagworte:
Clinical Research
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC5407719/
https://ncbi.nlm.nih.gov/pubmed/28096309
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1681/ASN.2016030343
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