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Conversion of alcohols to enantiopure amines through dual enzyme hydrogen-borrowing cascades
α-Chiral amines are key intermediates for the synthesis of a plethora of chemical compounds on industrial scale. Here we present a biocatalytic hydrogen-borrowing amination of primary and secondary alcohols that allows for the efficient and environmentally benign production of enantiopure amines. Th...
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| 出版年: | Science |
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| 主要な著者: | , , , , |
| フォーマット: | Artigo |
| 言語: | Inglês |
| 出版事項: |
2015
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| 主題: | |
| オンライン･アクセス: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4883652/ https://ncbi.nlm.nih.gov/pubmed/26404833 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1126/science.aac9283 |
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