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Conversion of alcohols to enantiopure amines through dual enzyme hydrogen-borrowing cascades
α-Chiral amines are key intermediates for the synthesis of a plethora of chemical compounds on industrial scale. Here we present a biocatalytic hydrogen-borrowing amination of primary and secondary alcohols that allows for the efficient and environmentally benign production of enantiopure amines. Th...
Gorde:
| Argitaratua izan da: | Science |
|---|---|
| Egile Nagusiak: | , , , , |
| Formatua: | Artigo |
| Hizkuntza: | Inglês |
| Argitaratua: |
2015
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| Gaiak: | |
| Sarrera elektronikoa: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4883652/ https://ncbi.nlm.nih.gov/pubmed/26404833 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1126/science.aac9283 |
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