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Identifying Allosteric Hotspots with Dynamics: Application to Inter- and Intra-species Conservation

The rapidly growing volume of data being produced by next-generation sequencing initiatives is enabling more in-depth analyses of conservation than previously possible. Deep sequencing is uncovering disease loci and regions under selective constraint, despite the fact that intuitive biophysical reas...

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Detalhes bibliográficos
Publicado no:Structure
Main Authors: Clarke, Declan, Sethi, Anurag, Li, Shantao, Kumar, Sushant, Chang, Richard W.F., Chen, Jieming, Gerstein, Mark
Formato: Artigo
Idioma:Inglês
Publicado em: 2016
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4883016/
https://ncbi.nlm.nih.gov/pubmed/27066750
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.str.2016.03.008
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