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Sulfation of lower chlorinated polychlorinated biphenyls increases their affinity for the major drug-binding sites of human serum albumin

The disposition of toxicants is often affected by their binding to serum proteins, of which the most abundant in humans is serum albumin (HSA). There is increasing interest in the toxicities of environmentally persistent polychlorinated biphenyls (PCBs) with lower numbers of chlorine atoms (LC-PCBs)...

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Detalhes bibliográficos
Publicado no:Environ Sci Technol
Main Authors: Rodriguez, Eric A., Li, Xueshu, Lehmler, Hans-Joachim, Robertson, Larry W., Duffel, Michael W.
Formato: Artigo
Idioma:Inglês
Publicado em: 2016
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4883002/
https://ncbi.nlm.nih.gov/pubmed/27116425
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/acs.est.6b00484
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