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GINSENOSIDE RB1 INHIBITS FIBRILLATION AND TOXICITY OF ALPHA-SYNUCLEIN AND DISAGGREGATES PREFORMED FIBRILS
Compelling evidence indicates that α-synuclein (α-syn) aggregation plays a central role in the pathogenesis of Parkinson's disease (PD) and other synucleinopathies. Identification of compounds that inhibit or reverse the aggregation process may thus represent a viable therapeutic strategy again...
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| Udgivet i: | Neurobiol Dis |
|---|---|
| Main Authors: | , , , , , , , , , , |
| Format: | Artigo |
| Sprog: | Inglês |
| Udgivet: |
2014
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| Fag: | |
| Online adgang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4882765/ https://ncbi.nlm.nih.gov/pubmed/25449909 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.nbd.2014.11.007 |
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