Inhibition of alpha-synuclein seeded fibril formation and toxicity by herbal medicinal extracts

BACKGROUND: Recent studies indicated that seeded fibril formation and toxicity of α-synuclein (α-syn) play a main role in the pathogenesis of certain diseases including Parkinson’s disease (PD), multiple system atrophy, and dementia with Lewy bodies. Therefore, examination of compounds that abolish...

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Pubblicato in:BMC Complement Med Ther
Autori principali: Ardah, Mustafa T., Ghanem, Simona S., Abdulla, Sara A., Lv, Guohua, Emara, Mohamed M., Paleologou, Katerina E., Vaikath, Nishant N., Lu, Jia-Hong, Li, Min, Vekrellis, Konstantinos, Eliezer, David, El-Agnaf, Omar M. A.
Natura: Artigo
Lingua:Inglês
Pubblicazione: BioMed Central 2020
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Research Article
Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC7076823/
https://ncbi.nlm.nih.gov/pubmed/32143619
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s12906-020-2849-1
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