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Inhibition of fatty acid synthase is protective in pulmonary hypertension
BACKGROUND AND PURPOSE: In pulmonary hypertension (PH), similar to cancer, there is altered energy metabolism, apoptosis resistance and cellular proliferation leading to pulmonary vascular remodelling. Proliferating cells exhibit higher rate of de novo fatty acid synthesis to provide lipids for memb...
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| Veröffentlicht in: | Br J Pharmacol |
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| Hauptverfasser: | , , , , |
| Format: | Artigo |
| Sprache: | Inglês |
| Veröffentlicht: |
John Wiley and Sons Inc.
2016
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| Schlagworte: | |
| Online Zugang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4882492/ https://ncbi.nlm.nih.gov/pubmed/27061087 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1111/bph.13495 |
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