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Electrogenic Steps Associated with Substrate Binding to the Neuronal Glutamate Transporter EAAC1

Glutamate transporters actively take up glutamate into the cell, driven by the co-transport of sodium ions down their transmembrane concentration gradient. It was proposed that glutamate binds to its binding site and is subsequently transported across the membrane in the negatively charged form. Wit...

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Bibliographische Detailangaben
Veröffentlicht in:J Biol Chem
Hauptverfasser: Tanui, Rose, Tao, Zhen, Silverstein, Nechama, Kanner, Baruch, Grewer, Christof
Format: Artigo
Sprache:Inglês
Veröffentlicht: American Society for Biochemistry and Molecular Biology 2016
Schlagworte:
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC4882452/
https://ncbi.nlm.nih.gov/pubmed/27044739
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M116.722470
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