Characterizing strain variation in engineered E. coli using a multi-omics based workflow

Understanding the complex interactions that occur between heterologous and native biochemical pathways represents a major challenge in metabolic engineering and synthetic biology. We present a workflow that integrates metabolomics, proteomics, and genome-scale models of Escherichia coli metabolism t...

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Publicat a:Cell Syst
Autors principals: Brunk, Elizabeth, George, Kevin W., Alonso-Gutierrez, Jorge, Thompson, Mitchell, Baidoo, Edward, Wang, George, Petzold, Christopher J., McCloskey, Douglas, Monk, Jonathan, Yang, Laurence, O’Brien, Edward J., Batth, Tanveer S., Martin, Hector Garcia, Feist, Adam, Adams, Paul D., Keasling, Jay D., Palsson, Bernhard O., Lee, Taek Soon
Format: Artigo
Idioma:Inglês
Publicat: 2016
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Article
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC4882250/
https://ncbi.nlm.nih.gov/pubmed/27211860
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.cels.2016.04.004
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