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Basic and applied uses of genome-scale metabolic network reconstructions of Escherichia coli

The genome-scale model (GEM) of metabolism in the bacterium Escherichia coli K-12 has been in development for over a decade and is now in wide use. GEM-enabled studies of E. coli have been primarily focused on six applications: (1) metabolic engineering, (2) model-driven discovery, (3) prediction of...

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Bibliografiske detaljer
Main Authors: McCloskey, Douglas, Palsson, Bernhard Ø, Feist, Adam M
Format: Artigo
Sprog:Inglês
Udgivet: European Molecular Biology Organization 2013
Fag:
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC3658273/
https://ncbi.nlm.nih.gov/pubmed/23632383
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/msb.2013.18
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