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Genome-scale reconstruction of the Lrp regulatory network in Escherichia coli

Broad-acting transcription factors (TFs) in bacteria form regulons. Here, we present a 4-step method to fully reconstruct the leucine-responsive protein (Lrp) regulon in Escherichia coli K-12 MG 1655 that regulates nitrogen metabolism. Step 1 is composed of obtaining high-resolution ChIP-chip data f...

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Detalhes bibliográficos
Main Authors: Cho, Byung-Kwan, Barrett, Christian L., Knight, Eric M., Park, Young Seoub, Palsson, Bernhard Ø.
Formato: Artigo
Idioma:Inglês
Publicado em: National Academy of Sciences 2008
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2614783/
https://ncbi.nlm.nih.gov/pubmed/19052235
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.0807227105
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