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A CRISPR Path to Engineering New Genetic Mouse Models for Cardiovascular Research

Previous efforts to target the mouse genome for the addition, subtraction, or substitution of biologically informative sequences required complex vector design and a series of arduous steps only a handful of labs could master. The facile and inexpensive clustered regularly interspaced short palindro...

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Bibliografske podrobnosti
izdano v:Arterioscler Thromb Vasc Biol
Main Authors: Miano, Joseph M., Zhu, Qiuyu Martin, Lowenstein, Charles J.
Format: Artigo
Jezik:Inglês
Izdano: 2016
Teme:
Online dostop:https://ncbi.nlm.nih.gov/pmc/articles/PMC4882230/
https://ncbi.nlm.nih.gov/pubmed/27102963
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1161/ATVBAHA.116.304790
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