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A CRISPR Path to Engineering New Genetic Mouse Models for Cardiovascular Research

Previous efforts to target the mouse genome for the addition, subtraction, or substitution of biologically informative sequences required complex vector design and a series of arduous steps only a handful of labs could master. The facile and inexpensive clustered regularly interspaced short palindro...

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Vydáno v:Arterioscler Thromb Vasc Biol
Hlavní autoři: Miano, Joseph M., Zhu, Qiuyu Martin, Lowenstein, Charles J.
Médium: Artigo
Jazyk:Inglês
Vydáno: 2016
Témata:
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC4882230/
https://ncbi.nlm.nih.gov/pubmed/27102963
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1161/ATVBAHA.116.304790
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