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A CRISPR Path to Engineering New Genetic Mouse Models for Cardiovascular Research

Previous efforts to target the mouse genome for the addition, subtraction, or substitution of biologically informative sequences required complex vector design and a series of arduous steps only a handful of labs could master. The facile and inexpensive clustered regularly interspaced short palindro...

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Veröffentlicht in:Arterioscler Thromb Vasc Biol
Hauptverfasser: Miano, Joseph M., Zhu, Qiuyu Martin, Lowenstein, Charles J.
Format: Artigo
Sprache:Inglês
Veröffentlicht: 2016
Schlagworte:
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC4882230/
https://ncbi.nlm.nih.gov/pubmed/27102963
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1161/ATVBAHA.116.304790
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