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Threonine 89 Is an Important Residue of Profilin-1 That Is Phosphorylatable by Protein Kinase A

OBJECTIVE: Dynamic regulation of actin cytoskeleton is at the heart of all actin-based cellular events. In this study, we sought to identify novel post-translational modifications of Profilin-1 (Pfn1), an important regulator of actin polymerization in cells. METHODOLOGY: We performed in vitro protei...

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Bibliographische Detailangaben
Veröffentlicht in:PLoS One
Hauptverfasser: Gau, David, Veon, William, Zeng, Xuemei, Yates, Nathan, Shroff, Sanjeev G., Koes, David R., Roy, Partha
Format: Artigo
Sprache:Inglês
Veröffentlicht: Public Library of Science 2016
Schlagworte:
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC4882052/
https://ncbi.nlm.nih.gov/pubmed/27228149
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0156313
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