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The VASP–profilin1 (Pfn1) interaction is critical for efficient cell migration and is regulated by cell–substrate adhesion in a PKA-dependent manner

Dynamic regulation of the actin cytoskeleton is an essential feature of cell motility. Action of Enabled (Ena)/vasodilator-stimulated phosphoprotein (VASP), a family of conserved actin-elongating proteins, is an important aspect of regulation of the actin cytoskeletal architecture at the leading edg...

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Detalhes bibliográficos
Publicado no:J Biol Chem
Main Authors: Gau, David, Veon, William, Shroff, Sanjeev G., Roy, Partha
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Biochemistry and Molecular Biology 2019
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6497960/
https://ncbi.nlm.nih.gov/pubmed/30814249
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.RA118.005255
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