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Loss of Profilin-1 Expression Enhances Breast Cancer Cell Motility by Ena/VASP Proteins
We previously showed that silencing profilin-1 (Pfn1) expression increases breast cancer cell motility, but the underlying mechanisms have not been explored. Herein, we demonstrate that loss of Pfn1 expression leads to slower but more stable lamellipodial protrusion thereby enhancing the net protrus...
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| Main Authors: | , , , , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
2009
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2990882/ https://ncbi.nlm.nih.gov/pubmed/19115233 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/jcp.21677 |
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