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Systemic Immunotherapy of Non–Muscle Invasive Mouse Bladder Cancer with Avelumab, an Anti–PD-L1 Immune Checkpoint Inhibitor

Bacillus Calmette-Guerin (BCG) is the standard of care for intravesical therapy for carcinoma in situ and non–muscle invasive, nonmetastatic human urothelial carcinoma. While the responsiveness to this immunotherapeutic is believed to be linked with (i) a high number of somatic mutations and (ii) a...

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Vydáno v:Cancer Immunol Res
Hlavní autoři: Vandeveer, Amanda J., Fallon, Jonathan K., Tighe, Robert, Sabzevari, Helen, Schlom, Jeffrey, Greiner, John W.
Médium: Artigo
Jazyk:Inglês
Vydáno: 2016
Témata:
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC4881865/
https://ncbi.nlm.nih.gov/pubmed/26921031
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1158/2326-6066.CIR-15-0176
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