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Systemic Immunotherapy of Non–Muscle Invasive Mouse Bladder Cancer with Avelumab, an Anti–PD-L1 Immune Checkpoint Inhibitor

Bacillus Calmette-Guerin (BCG) is the standard of care for intravesical therapy for carcinoma in situ and non–muscle invasive, nonmetastatic human urothelial carcinoma. While the responsiveness to this immunotherapeutic is believed to be linked with (i) a high number of somatic mutations and (ii) a...

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Dettagli Bibliografici
Pubblicato in:Cancer Immunol Res
Autori principali: Vandeveer, Amanda J., Fallon, Jonathan K., Tighe, Robert, Sabzevari, Helen, Schlom, Jeffrey, Greiner, John W.
Natura: Artigo
Lingua:Inglês
Pubblicazione: 2016
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Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC4881865/
https://ncbi.nlm.nih.gov/pubmed/26921031
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1158/2326-6066.CIR-15-0176
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