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Systemic Immunotherapy of Non–Muscle Invasive Mouse Bladder Cancer with Avelumab, an Anti–PD-L1 Immune Checkpoint Inhibitor

Bacillus Calmette-Guerin (BCG) is the standard of care for intravesical therapy for carcinoma in situ and non–muscle invasive, nonmetastatic human urothelial carcinoma. While the responsiveness to this immunotherapeutic is believed to be linked with (i) a high number of somatic mutations and (ii) a...

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Detalhes bibliográficos
Publicado no:Cancer Immunol Res
Main Authors: Vandeveer, Amanda J., Fallon, Jonathan K., Tighe, Robert, Sabzevari, Helen, Schlom, Jeffrey, Greiner, John W.
Formato: Artigo
Idioma:Inglês
Publicado em: 2016
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4881865/
https://ncbi.nlm.nih.gov/pubmed/26921031
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1158/2326-6066.CIR-15-0176
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