Novel Types of Small RNA Exhibit Sequence- and Target-dependent Angiogenesis Suppression Without Activation of Toll-like Receptor 3 in an Age-related Macular Degeneration (AMD) Mouse Model

RNA interference (RNAi) has become a powerful tool for suppressing gene expression in vitro and in vivo. A great deal of evidence has demonstrated the potential for the use of synthetic small interfering RNAs (siRNAs) as therapeutic agents. However, the application of siRNA to clinical medicine is s...

Täydet tiedot

Tallennettuna:
Bibliografiset tiedot
Julkaisussa:Mol Ther Nucleic Acids
Päätekijät: Takanashi, Masakatsu, Sudo, Katsuko, Ueda, Shinobu, Ohno, Shin-Ichiro, Yamada, Yuko, Osakabe, Yasuhiro, Goto, Hiroshi, Matsunaga, Yoshimichi, Ishikawa, Akio, Usui, Yoshihiko, Kuroda, Masahiko
Aineistotyyppi: Artigo
Kieli:Inglês
Julkaistu: Nature Publishing Group 2015
Aiheet:
Original Article
Linkit:https://ncbi.nlm.nih.gov/pmc/articles/PMC4881762/
https://ncbi.nlm.nih.gov/pubmed/26484944
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/mtna.2015.34
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