Novel Types of Small RNA Exhibit Sequence- and Target-dependent Angiogenesis Suppression Without Activation of Toll-like Receptor 3 in an Age-related Macular Degeneration (AMD) Mouse Model

RNA interference (RNAi) has become a powerful tool for suppressing gene expression in vitro and in vivo. A great deal of evidence has demonstrated the potential for the use of synthetic small interfering RNAs (siRNAs) as therapeutic agents. However, the application of siRNA to clinical medicine is s...

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Bibliografische gegevens
Gepubliceerd in:Mol Ther Nucleic Acids
Hoofdauteurs: Takanashi, Masakatsu, Sudo, Katsuko, Ueda, Shinobu, Ohno, Shin-Ichiro, Yamada, Yuko, Osakabe, Yasuhiro, Goto, Hiroshi, Matsunaga, Yoshimichi, Ishikawa, Akio, Usui, Yoshihiko, Kuroda, Masahiko
Formaat: Artigo
Taal:Inglês
Gepubliceerd in: Nature Publishing Group 2015
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Original Article
Online toegang:https://ncbi.nlm.nih.gov/pmc/articles/PMC4881762/
https://ncbi.nlm.nih.gov/pubmed/26484944
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/mtna.2015.34
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