Systemically Injected Exosomes Targeted to EGFR Deliver Antitumor MicroRNA to Breast Cancer Cells

Despite the therapeutic potential of nucleic acid drugs, their clinical application has been limited in part by a lack of appropriate delivery systems. Exosomes or microvesicles are small endosomally derived vesicles that are secreted by a variety of cell types and tissues. Here, we show that exosom...

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Detalhes bibliográficos
Main Authors: Ohno, Shin-ichiro, Takanashi, Masakatsu, Sudo, Katsuko, Ueda, Shinobu, Ishikawa, Akio, Matsuyama, Nagahisa, Fujita, Koji, Mizutani, Takayuki, Ohgi, Tadaaki, Ochiya, Takahiro, Gotoh, Noriko, Kuroda, Masahiko
Formato: Artigo
Idioma:Inglês
Publicado em: Nature Publishing Group 2013
Assuntos:
Original Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3538304/
https://ncbi.nlm.nih.gov/pubmed/23032975
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/mt.2012.180
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