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Chlorogenic Acid Activates CFTR-Mediated Cl(-) Secretion in Mice and Humans: Therapeutic Implications for Chronic Rhinosinusitis

OBJECTIVES: Salubrious effects of the green coffee bean are purportedly secondary to high concentrations of chlorogenic acid. Chlorogenic acid has a molecular structure similar to bioflavonoids that activate transepithelial Cl(-) transport in sinonasal epithelia. In contrast to flavonoids, the drug...

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Dades bibliogràfiques
Publicat a:Otolaryngol Head Neck Surg
Autors principals: Illing, Elisa, Cho, Do-Yeon, Zhang, Shaoyan, Skinner, Daniel F., Dunlap, Quinn A., Sorscher, Eric J., Woodworth, Bradford A.
Format: Artigo
Idioma:Inglês
Publicat: 2015
Matèries:
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC4881747/
https://ncbi.nlm.nih.gov/pubmed/26019132
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1177/0194599815586720
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