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Chlorogenic Acid Activates CFTR-Mediated Cl(-) Secretion in Mice and Humans: Therapeutic Implications for Chronic Rhinosinusitis
OBJECTIVES: Salubrious effects of the green coffee bean are purportedly secondary to high concentrations of chlorogenic acid. Chlorogenic acid has a molecular structure similar to bioflavonoids that activate transepithelial Cl(-) transport in sinonasal epithelia. In contrast to flavonoids, the drug...
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| Publicado no: | Otolaryngol Head Neck Surg |
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| Main Authors: | , , , , , , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
2015
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4881747/ https://ncbi.nlm.nih.gov/pubmed/26019132 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1177/0194599815586720 |
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