Resveratrol and ivacaftor are additive G551D CFTR channel potentiators: Therapeutic implications for cystic fibrosis sinus disease

INTRODUCTION: Mutations in the Cystic Fibrosis Transmembrane Conductance Regulator (CFTR) gene result in defective Cl(−) transport and cause chronic bacterial infections in the upper and lower airways of cystic fibrosis (CF) patients. Ivacaftor is a CFTR potentiator that improves Cl(−) transport in...

Celý popis

Uloženo v:
Podrobná bibliografie
Vydáno v:Int Forum Allergy Rhinol
Hlavní autoři: Cho, Do-Yeon, Zhang, Shaoyan, Lazrak, Ahmed, Grayson, Jessica W., Peña Garcia, Jaime A., Skinner, Daniel F., Lim, Dong Jin, Mackey, Calvin, Banks, Catherine, Matalon, Sadis, Woodworth, Bradford A.
Médium: Artigo
Jazyk:Inglês
Vydáno: 2018
Témata:
Article
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC6318032/
https://ncbi.nlm.nih.gov/pubmed/30152192
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/alr.22202
Tagy: Přidat tag
Žádné tagy, Buďte první, kdo otaguje tento záznam!

Podobné jednotky