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Downregulation of Runx2 by 1,25-Dihydroxyvitamin D(3) Induces the Transdifferentiation of Osteoblasts to Adipocytes
1,25-Dihydroxyvitamin D(3) (1,25(OH)(2)D(3)) indirectly stimulates bone formation, but little is known about its direct effect on bone formation. In this study, we observed that 1,25(OH)(2)D(3) enhances adipocyte differentiation, but inhibits osteoblast differentiation during osteogenesis. The posit...
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| Udgivet i: | Int J Mol Sci |
|---|---|
| Main Authors: | , , , , , |
| Format: | Artigo |
| Sprog: | Inglês |
| Udgivet: |
MDPI
2016
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| Fag: | |
| Online adgang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4881589/ https://ncbi.nlm.nih.gov/pubmed/27213351 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3390/ijms17050770 |
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