GATA4 negatively regulates osteoblast differentiation by downregulation of Runx2

Osteoblasts are specialized mesenchymal cells that are responsible for bone formation. In this study, we examine the role of GATA4 in osteoblast differentiation. GATA4 was abundantly expressed in preosteoblast cells and gradually down-regulated during osteoblast differentiation. Overexpression of GA...

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Detalhes bibliográficos
Main Authors: Song, Insun, Kim, Kabsun, Kim, Jung Ha, Lee, Young-Kyoung, Jung, Hyun-Jung, Byun, Hae-Ok, Yoon, Gyesoon, Kim, Nacksung
Formato: Artigo
Idioma:Inglês
Publicado em: Korean Society for Biochemistry and Molecular Biology 2014
Assuntos:
Research Articles
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4206719/
https://ncbi.nlm.nih.gov/pubmed/24355298
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.5483/BMBRep.2014.47.8.225
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