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Downregulation of Runx2 by 1,25-Dihydroxyvitamin D(3) Induces the Transdifferentiation of Osteoblasts to Adipocytes

1,25-Dihydroxyvitamin D(3) (1,25(OH)(2)D(3)) indirectly stimulates bone formation, but little is known about its direct effect on bone formation. In this study, we observed that 1,25(OH)(2)D(3) enhances adipocyte differentiation, but inhibits osteoblast differentiation during osteogenesis. The posit...

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Bibliografische gegevens
Gepubliceerd in:Int J Mol Sci
Hoofdauteurs: Kim, Jung Ha, Seong, Semun, Kim, Kabsun, Kim, Inyoung, Jeong, Byung-Chul, Kim, Nacksung
Formaat: Artigo
Taal:Inglês
Gepubliceerd in: MDPI 2016
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Online toegang:https://ncbi.nlm.nih.gov/pmc/articles/PMC4881589/
https://ncbi.nlm.nih.gov/pubmed/27213351
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3390/ijms17050770
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