Simultaneous Denoising, Deconvolution, and Demixing of Calcium Imaging Data

We present a modular approach for analyzing calcium imaging recordings of large neuronal ensembles. Our goal is to simultaneously identify the locations of the neurons, demix spatially overlapping components, and denoise and deconvolve the spiking activity from the slow dynamics of the calcium indic...

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Publicado en:Neuron
Autores principales: Pnevmatikakis, Eftychios A., Soudry, Daniel, Gao, Yuanjun, Machado, Timothy A., Merel, Josh, Pfau, David, Reardon, Thomas, Mu, Yu, Lacefield, Clay, Yang, Weijian, Ahrens, Misha, Bruno, Randy, Jessell, Thomas M., Peterka, Darcy S., Yuste, Rafael, Paninski, Liam
Formato: Artigo
Lenguaje:Inglês
Publicado: 2016
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Article
Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC4881387/
https://ncbi.nlm.nih.gov/pubmed/26774160
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.neuron.2015.11.037
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