Simultaneous Denoising, Deconvolution, and Demixing of Calcium Imaging Data

We present a modular approach for analyzing calcium imaging recordings of large neuronal ensembles. Our goal is to simultaneously identify the locations of the neurons, demix spatially overlapping components, and denoise and deconvolve the spiking activity from the slow dynamics of the calcium indic...

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Bibliografiske detaljer
Udgivet i:Neuron
Main Authors: Pnevmatikakis, Eftychios A., Soudry, Daniel, Gao, Yuanjun, Machado, Timothy A., Merel, Josh, Pfau, David, Reardon, Thomas, Mu, Yu, Lacefield, Clay, Yang, Weijian, Ahrens, Misha, Bruno, Randy, Jessell, Thomas M., Peterka, Darcy S., Yuste, Rafael, Paninski, Liam
Format: Artigo
Sprog:Inglês
Udgivet: 2016
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Article
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC4881387/
https://ncbi.nlm.nih.gov/pubmed/26774160
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.neuron.2015.11.037
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