Simultaneous Denoising, Deconvolution, and Demixing of Calcium Imaging Data

We present a modular approach for analyzing calcium imaging recordings of large neuronal ensembles. Our goal is to simultaneously identify the locations of the neurons, demix spatially overlapping components, and denoise and deconvolve the spiking activity from the slow dynamics of the calcium indic...

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Detalhes bibliográficos
Publicado no:Neuron
Main Authors: Pnevmatikakis, Eftychios A., Soudry, Daniel, Gao, Yuanjun, Machado, Timothy A., Merel, Josh, Pfau, David, Reardon, Thomas, Mu, Yu, Lacefield, Clay, Yang, Weijian, Ahrens, Misha, Bruno, Randy, Jessell, Thomas M., Peterka, Darcy S., Yuste, Rafael, Paninski, Liam
Formato: Artigo
Idioma:Inglês
Publicado em: 2016
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Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4881387/
https://ncbi.nlm.nih.gov/pubmed/26774160
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.neuron.2015.11.037
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