Simultaneous Denoising, Deconvolution, and Demixing of Calcium Imaging Data

We present a modular approach for analyzing calcium imaging recordings of large neuronal ensembles. Our goal is to simultaneously identify the locations of the neurons, demix spatially overlapping components, and denoise and deconvolve the spiking activity from the slow dynamics of the calcium indic...

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Vydáno v:Neuron
Hlavní autoři: Pnevmatikakis, Eftychios A., Soudry, Daniel, Gao, Yuanjun, Machado, Timothy A., Merel, Josh, Pfau, David, Reardon, Thomas, Mu, Yu, Lacefield, Clay, Yang, Weijian, Ahrens, Misha, Bruno, Randy, Jessell, Thomas M., Peterka, Darcy S., Yuste, Rafael, Paninski, Liam
Médium: Artigo
Jazyk:Inglês
Vydáno: 2016
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Article
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC4881387/
https://ncbi.nlm.nih.gov/pubmed/26774160
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.neuron.2015.11.037
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