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Impact of Different Promoters on Episomal Vectors Harbouring Characteristic Motifs of Matrix Attachment Regions

We previously demonstrated that the characteristic sequence of matrix attachment regions (MARs) allows transgenes to be maintained episomally in CHO cells. In the present study, six commonly used promoters from human cytomegalovirus major immediate-early (CMV), simian vacuolating virus 40 (SV40), Ro...

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Détails bibliographiques
Publié dans:Sci Rep
Auteurs principaux: Wang, Xiao-Yin, Zhang, Jun-He, Zhang, Xi, Sun, Qiu-Li, Zhao, Chun-Peng, Wang, Tian-Yun
Format: Artigo
Langue:Inglês
Publié: Nature Publishing Group 2016
Sujets:
Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC4881036/
https://ncbi.nlm.nih.gov/pubmed/27226236
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/srep26446
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