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Enhanced whole exome sequencing by higher DNA insert lengths
BACKGROUND: Whole exome sequencing (WES) has been proven to serve as a valuable basis for various applications such as variant calling and copy number variation (CNV) analyses. For those analyses the read coverage should be optimally balanced throughout protein coding regions at sufficient read dept...
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| Publicado en: | BMC Genomics |
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| Autores principales: | , , , , , , |
| Formato: | Artigo |
| Lenguaje: | Inglês |
| Publicado: |
BioMed Central
2016
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| Materias: | |
| Acceso en línea: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4880973/ https://ncbi.nlm.nih.gov/pubmed/27225215 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s12864-016-2698-y |
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