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Enhanced whole exome sequencing by higher DNA insert lengths

BACKGROUND: Whole exome sequencing (WES) has been proven to serve as a valuable basis for various applications such as variant calling and copy number variation (CNV) analyses. For those analyses the read coverage should be optimally balanced throughout protein coding regions at sufficient read dept...

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Dades bibliogràfiques
Publicat a:BMC Genomics
Autors principals: Pommerenke, Claudia, Geffers, Robert, Bunk, Boyke, Bhuju, Sabin, Eberth, Sonja, Drexler, Hans G., Quentmeier, Hilmar
Format: Artigo
Idioma:Inglês
Publicat: BioMed Central 2016
Matèries:
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC4880973/
https://ncbi.nlm.nih.gov/pubmed/27225215
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s12864-016-2698-y
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