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The MYC 3′ Wnt-Responsive Element Drives Oncogenic MYC Expression in Human Colorectal Cancer Cells

Mutations in components of the Wnt/β-catenin signaling pathway drive colorectal cancer (CRC) by deregulating expression of downstream target genes including the c-MYC proto-oncogene (MYC). The critical regulatory DNA enhancer elements that control oncogenic MYC expression in CRC have yet to be fully...

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Détails bibliographiques
Publié dans:Cancers (Basel)
Auteurs principaux: Rennoll, Sherri A., Eshelman, Melanie A., Raup-Konsavage, Wesley M., Kawasawa, Yuka Imamura, Yochum, Gregory S.
Format: Artigo
Langue:Inglês
Publié: MDPI 2016
Sujets:
Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC4880869/
https://ncbi.nlm.nih.gov/pubmed/27223305
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3390/cancers8050052
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