Uncoupling of the DNA topoisomerase and replication activities of an initiator protein.
The replication initiator proteins encoded by the pT181 and related plasmids have sequence-specific DNA binding and topoisomerase activities. These proteins create a site-specific nick in one strand of the DNA at the origin of replication that serves as a primer for the initiation of replication. To...
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| Published in: | Proc Natl Acad Sci U S A |
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| Main Authors: | , , |
| Format: | Artigo |
| Language: | Inglês |
| Published: |
National Academy of Sciences
1992
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| Subjects: | |
| Online Access: | https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC48808/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/1313580/ https://ncbi.nlm.nih.govhttps://doi.org/10.1073/pnas.89.7.3083 |
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