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High resistance to cisplatin in human ovarian cancer cell lines is associated with marked increase of glutathione synthesis.

Exposure of human ovarian tumor cell lines to cisplatin led to development of cell lines that exhibited increasing degrees of drug resistance, which were closely correlated with increase of the levels of cellular glutathione. Cell lines were obtained that showed 30- to 1000-fold increases in resista...

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書誌詳細
主要な著者: Godwin, A K, Meister, A, O'Dwyer, P J, Huang, C S, Hamilton, T C, Anderson, M E
フォーマット: Artigo
言語:Inglês
出版事項: 1992
主題:
オンライン・アクセス:https://ncbi.nlm.nih.gov/pmc/articles/PMC48805/
https://ncbi.nlm.nih.gov/pubmed/1348364
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