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Evolution of Thermophilic DNA Polymerases for the Recognition and Amplification of C2’-Modified DNA
The PCR amplification of oligonucleotides enables the evolution of sequences called aptamers that bind specific targets with antibody-like affinity. However, the use of these aptamers is limited in many applications by nuclease-mediated degradation. In contrast, oligonucleotides that are modified at...
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| Vydáno v: | Nat Chem |
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| Hlavní autoři: | , , , , , |
| Médium: | Artigo |
| Jazyk: | Inglês |
| Vydáno: |
2016
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| Témata: | |
| On-line přístup: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4880425/ https://ncbi.nlm.nih.gov/pubmed/27219699 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/nchem.2493 |
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