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Palladium-Catalyzed Benzylic C–H Arylation of Azaarylmethylamines

[Image: see text] A direct C–H functionalization approach to produce aryl(azaaryl)methylamines from azaarylmethylamines without directing groups is described. Under conditions where the azaarylmethylamines’ C–H is reversibly deprotonated, a Pd(OAc)(2)/NIXANTPHOS-based catalyst couples the resulting...

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Bibliografiske detaljer
Udgivet i:Org Lett
Main Authors: Kim, Byeong-Seon, Jiménez, Jacqueline, Gao, Feng, Walsh, Patrick J.
Format: Artigo
Sprog:Inglês
Udgivet: 2015
Fag:
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC4880366/
https://ncbi.nlm.nih.gov/pubmed/26576005
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/acs.orglett.5b02898
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