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Lys63/Met1-hybrid ubiquitin chains are commonly formed during the activation of innate immune signalling

We have reported previously that activation of the MyD88-signaling network rapidly induces the formation of hybrid ubiquitin chains containing both Lys63-linked and Met1-linked ubiquitin (Ub) oligomers, some of which are attached covalently to Interleukin Receptor Associated kinase 1. Here we show t...

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Detalhes bibliográficos
Publicado no:Biochem Biophys Res Commun
Main Authors: Emmerich, Christoph H., Bakshi, Siddharth, Kelsall, Ian R., Ortiz-Guerrero, Juanma, Shpiro, Natalia, Cohen, Philip
Formato: Artigo
Idioma:Inglês
Publicado em: Elsevier 2016
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4880150/
https://ncbi.nlm.nih.gov/pubmed/27133719
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.bbrc.2016.04.141
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