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Activation of the canonical IKK complex by K63/M1-linked hybrid ubiquitin chains
Polyubiquitin (pUb) chains formed between the C terminus of ubiquitin and lysine 63 (K63) or methionine 1 (M1) of another ubiquitin have been implicated in the activation of the canonical IκB kinase (IKK) complex. Here, we demonstrate that nearly all of the M1-pUb chains formed in response to interl...
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| Main Authors: | , , , , , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
National Academy of Sciences
2013
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3780889/ https://ncbi.nlm.nih.gov/pubmed/23986494 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.1314715110 |
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