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A Multi-state Model for Designing Clinical Trials for Testing Overall Survival Allowing for Crossover after Progression
In designing a clinical trial for comparing two or more treatments with respect to overall survival (OS), a proportional hazards assumption is commonly made. However, in many cancer clinical trials, patients pass through various disease states prior to death and because of this may receive treatment...
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| Publicado no: | Stat Biopharm Res |
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| Main Authors: | , , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
2016
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4879617/ https://ncbi.nlm.nih.gov/pubmed/27239255 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1080/19466315.2015.1093539 |
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