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Multi-Crossover Randomized Controlled Trial Designs in Alzheimer’s Disease

Conventional parallel group randomized controlled clinical trials (RCT) in Alzheimer’s disease (AD) are too large, long, expensive and insensitive to clinical change to meet the urgent need for an effective treatment. While providing good evidence for a treatment’s benefit, parallel group RCTs in AD...

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Detalhes bibliográficos
Publicado no:Ann Neurol
Main Authors: Arnold, Steven E., Betensky, Rebecca A.
Formato: Artigo
Idioma:Inglês
Publicado em: 2018
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6481185/
https://ncbi.nlm.nih.gov/pubmed/30014506
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/ana.25280
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