Effects of the Insulin Sensitizer Metformin in Alzheimer’s Disease: Pilot Data from a Randomized Placebo-Controlled Crossover Study

Epidemiological studies have identified a robust association between Type II Diabetes Mellitus (T2DM) and Alzheimer’s Disease (AD), and neurobiological studies have suggested the presence of central nervous system (CNS) insulin resistance in individuals with AD. Given this association, we hypothesiz...

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Detalhes bibliográficos
Publicado no:Alzheimer Dis Assoc Disord
Main Authors: Koenig, Aaron M., Mechanic-Hamilton, Dawn, Xie, Sharon X., Combs, Martha F., Cappola, Anne R., Xie, Long, Detre, John A., Wolk, David A., Arnold, Steven E.
Formato: Artigo
Idioma:Inglês
Publicado em: 2017
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Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5476214/
https://ncbi.nlm.nih.gov/pubmed/28538088
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1097/WAD.0000000000000202
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